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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Abcam/Recombinant human EGF protein (Active) (ab259398)/1/Active) (ab259398
产品编号:Active)(ab259398
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Abcam
公      司:Abcam
公司分类:
Abcam/Recombinant human EGF protein (Active) (ab259398)/1/Active) (ab259398
商品介绍

Description

  • Product name

    Recombinant human EGF protein (Active)See all EGF proteins and peptides
  • Biological activity

    Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant Proliferation of BALB / 3T3 cells is 0.99 ng/mL corresponding to a Specific Activity of 1.01 x 106IU/mg.

  • Purity

    >= 95% SDS-PAGE.>= 95 % HPLC.
  • Endotoxin level

    <>
  • Expression system

    HEK 293 cells
  • Accession

    P01133
  • Protein length

    Full length protein
  • Animal free

    Yes
  • Carrier free

    Yes
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      NSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW ELR
    • Predicted molecular weight

      6 kDa
    • Amino acids

      971 to 1023
    • Additional sequence information

      N-terminal glycine. Full-length mature EGF chain.

Associated products

    Specifications

    Our Abpromise guarantee covers the use ofab259398in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Mass Spectrometry

      HPLC

      SDS-PAGE

      Cell Culture

      Functional Studies

    • Form

      Lyophilized
    • Additional notes

      This protein is filter sterilised prior to aliquoting and lyophilisation. All aliquoting and lyophilisation steps are performed in a sterile environment

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Store at Room Temperature.

      Information available upon request.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute with Phosphate Buffered saline.Reconstituted protein stable at -80C for 12 months or 4C for 1 week.

    General Info

    • Alternative names

      • Beta urogastrone
      • beta-urogastrone
      • EGF
      • EGF_HUMAN
      • Epidermal growth factor
      • HOMG4
      • OTTHUMP00000219721
      • OTTHUMP00000219722
      • Pro epidermal growth factor
      • URG
      • Urogastrone
      see all
    • Function

      EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
    • Tissue specificity

      Expressed in kidney, salivary gland, cerebrum and prostate.
    • Involvement in disease

      Hypomagnesemia 4
    • Sequence similarities

      Contains 9 EGF-like domains.Contains 9 LDL-receptor class B repeats.
    • Post-translationalmodifications

      O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
    • Cellular localization

      Membrane.
    • Information by UniProt
    品牌介绍

    Abcam 位于英国的剑桥科学园,成立于1998年,专门生产和分销研究型抗体。在线目录 (www.abcam.cn) 已有超过 120,000 种抗体和试剂,并不断添加,供应予全球百多个国家。
    为使研究员更容易找到蛋白质研究试剂产品,在2011并购了美国的 MitoSciences 公司,加强了免疫分析方面的产品供应;同年也并购了英国的 Ascent Scientific 公司,开展了生化试剂的供应。在2012年并购了美国的 Epitomics 公司,成为一家有领导地位的 RabMAbs® 供应商。
    Abcam 的目标是给世界上最好的抗体建立最大的在线目录,为各地科学家提供尖端产品,成为各国科学界的重要伙伴,为所有产品提供技术支持来使客户获得预期的结果,为提供高质量的抗体来指向尽可能多的靶蛋白,尽所能在尽可能多的应用和物种中检测每种抗体。
    Abcam 专注于特定的研究领域,包括肿瘤研究、心血管研究、染色质和基因调控研究、免疫学、内参对照、微生物学、神经科学、细胞核信号转导研究、RNAi 研究、干细胞研究、亚细胞标记物等。

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