For non-profit organizations, please use discount code ACCESS-TMA72 for a discounted price.
Product is available in three sizes:
Small - 2.5x106 cells/vialLarge - 5x106 cells/vialMultipack - 4 x Large vials - total 20x106 cells
Introducing the ioSkeletal Myocytes, generated from human induced pluripotent stem cells (iPSCs) using opti-ox, a precise cellular reprogramming technology. Human stem cells, within days, convert into consistent and reliable skeletal myocytes, providing a high-quality human model for research, disease modelling and HTS.
ioSkeletal Myocytesdemonstrate robust expression of key proteins of myofilaments (Desmin, Titin, Troponin, Myosin Heavy Chain, Dystrophin), coupled with the transition from immature (MYH3 and MYH8) to mature myosin heavy chain isoforms (MYH1) in a time dependent manner. By Day 10 post revival, skeletal myocytes form striated multinucleated myocytes that contract in response to acetylcholine.
Human skeletal myocytes are available at scale, easy to culture and ready for experiments within days, providing a reliable model for the study of muscle, neuromuscular and associated metabolic disorders.
In partnership with bit.bio
Karyotype:Normal
Seeding Density:100,000 cells/cm2
Seeding compatibility:6-, 12-, 24- and 96-well compatible
Quality control:Sterility, ICC and gene expression analysis
Research applications: Muscle research, Neuromuscular junction Research, Metabolic research, Drug development, Genetic screening (e.g. CRISPR screening), Contractions assays
This product is subject to limited use licenses from iPS Academia Japan Inc, TET Systems GmbH, ERS Genomics Limited and Sigma-Aldrich Co. LLC and is developed with Bit Bio patented technology. For full details of the licenses and patents please refer to ourlimited use license and patent pages.
Abcam 位于英国的剑桥科学园,成立于1998年,专门生产和分销研究型抗体。在线目录 (www.abcam.cn) 已有超过 120,000 种抗体和试剂,并不断添加,供应予全球百多个国家。
为使研究员更容易找到蛋白质研究试剂产品,在2011并购了美国的 MitoSciences 公司,加强了免疫分析方面的产品供应;同年也并购了英国的 Ascent Scientific 公司,开展了生化试剂的供应。在2012年并购了美国的 Epitomics 公司,成为一家有领导地位的 RabMAbs® 供应商。
Abcam 的目标是给世界上最好的抗体建立最大的在线目录,为各地科学家提供尖端产品,成为各国科学界的重要伙伴,为所有产品提供技术支持来使客户获得预期的结果,为提供高质量的抗体来指向尽可能多的靶蛋白,尽所能在尽可能多的应用和物种中检测每种抗体。
Abcam 专注于特定的研究领域,包括肿瘤研究、心血管研究、染色质和基因调控研究、免疫学、内参对照、微生物学、神经科学、细胞核信号转导研究、RNAi 研究、干细胞研究、亚细胞标记物等。