Abcam/FirePlex miRNA Panel - Kidney Toxicity (ab219508)/1 x 48 tests/ab219508,Abcam,,Abcam,+,,Array.Array蚂蚁淘厂家直采.

产品名称：Abcam/FirePlex miRNA Panel - Kidney Toxicity (ab219508)/1 x 48 tests/ab219508

产品编号：ab219508

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>聚合物>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： Abcam

公司：Abcam

公司分类：

商品介绍

Product name
FirePlex miRNA Panel- Kidney Toxicity
Detection method
Flow cytometry-fluorescent
Assay type
Multiplex
Assay time
4h00m
Species reactivity
Reacts with:Mouse, Rat, Human
Product overview
Multiplex miRNA Assay - Kidney Toxicity Panel (ab219508) are the FirePlex® particles designedto profile up to 65 literature curated miRNA for kidney injury and toxicity,miRNAs that have been demonstrated in multiple peer-reviewed studies to be differentially regulated as a part of kidney toxicity or acute kidney injury.
NOTE: FirePlex miRNA panels require the purchase of a Run Buffer. Use our FirePlex Cytometer Setup Kit V2 (ab245835)to select the most appropriate Run Buffer for your flow cytometer.
Our multiplex miRNA assays use our FirePlex^®particle technology to profile up to 65 miRNAs per well. With the same sensitivity as PCR, they can be used either directlywith 10 µL of biofluids such as serum or plasma with no need for RNA purification; or with 100 pg of purified RNA.
Find a full list of validated sample types, and learn more about the performance and requirements of these assays,here.
These miRNAs have been chosen based on a detailed study of data in peer-reviewed journals and exhibit differential regulation in plasma, serum, urine, isolated exosomes or total RNA from kidney or kidney-derived cell lines.
Included in the panel are general markers for multiple kidney-related diseases, markers specific to specific kidney states or treatment responses, markers that may indicate hemolysis contamination in isolated plasma/serum/exosomes and internal controls are included to validate assay performance.
It is important to use the normalization procedure in the FirePlex^® Analysis Workbench Softwareto identify the miRNAs that can optimally be used for normalization with your samples. Three miRNAs that are likely to be stably expressed in biofluid samples and may be suitable have been included in this panel.

Notes

To use this product researchers must also purchase the appropriate Core Reagent Kit, either ab218365 for use with purified RNA or ab218342 for use withbiofluids.

FirePlex^® is a registered trade mark in the United States and is an unregistered trade mark elsewhere.

** Hsa = Homo sapiens (human), Mmu = Mus musculus (mouse), Rno = Rattus norvegicus (rat), Ath = Arabidopsis thaliana (arabidposis), Oan = Ornithorhynchus anatinus (platypus), Cel = Caenorhabditis elegans (worm).

#	miRNA 21 name	miRNA Sequence (miRBase V21)	Sequence homology **	MIMAT ID
1	hsa-let-7c-5p	UGAGGUAGUAGGUUGUAUGGUU	Hu, Ms, Rt	MIMAT0000064
2	hsa-let-7e-5p	UGAGGUAGGAGGUUGUAUAGUU	Hu, Ms, Rt	MIMAT0000066
3	hsa-let-7g-5p	UGAGGUAGUAGUUUGUACAGUU	Hu, Ms, Rt	MIMAT0000414
4	hsa-miR-100-5p	AACCCGUAGAUCCGAACUUGUG	Hu, Ms, Rt	MIMAT0000098
5	hsa-miR-10a-5p	UACCCUGUAGAUCCGAAUUUGUG	Hu, Ms, Rt	MIMAT0000253
6	hsa-miR-122-5p	UGGAGUGUGACAAUGGUGUUUG	Hu, Ms, Rt	MIMAT0000421
7	hsa-miR-125b-5p	UCCCUGAGACCCUAACUUGUGA	Hu, Ms, Rt	MIMAT0000423
8	hsa-miR-126-3p	UCGUACCGUGAGUAAUAAUGCG	Hu, Ms, Rt	MIMAT0000445
9	hsa-miR-130a-3p	CAGUGCAAUGUUAAAAGGGCAU	Hu, Ms, Rt	MIMAT0000425
10	hsa-miR-130b-3p	CAGUGCAAUGAUGAAAGGGCAU	Hu, Ms, Rt	MIMAT0000691
11	hsa-miR-132-3p	UAACAGUCUACAGCCAUGGUCG	Hu, Ms, Rt	MIMAT0000426
12	hsa-miR-134-5p	UGUGACUGGUUGACCAGAGGGG	Hu, Ms, Rt	MIMAT0000447
13	hsa-miR-138-5p	AGCUGGUGUUGUGAAUCAGGCCG	Hu, Ms, Rt	MIMAT0000430
14	hsa-miR-140-3p	UACCACAGGGUAGAACCACGG	Hu, Ms, Rt	MIMAT0004597
15	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA	Hu, Ms, Rt	MIMAT0000434
16	hsa-miR-143-3p	UGAGAUGAAGCACUGUAGCUC	Hu,Ms	MIMAT0000435
17	hsa-miR-145-5p	GUCCAGUUUUCCCAGGAAUCCCU	Hu, Ms, Rt	MIMAT0000437
18	hsa-miR-146a-5p	UGAGAACUGAAUUCCAUGGGUU	Hu, Ms, Rt	MIMAT0000449
19	hsa-miR-146b-5p	UGAGAACUGAAUUCCAUAGGCU	Hu,Ms	MIMAT0002809
20	mmu-miR-155-5p	UUAAUGCUAAUUGUGAUAGGGGU	Ms, Rt	MIMAT0000165
21	hsa-miR-15a-5p	UAGCAGCACAUAAUGGUUUGUG	Hu,Ms	MIMAT0000068
22	hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	Hu, Ms, Rt	MIMAT0000417
23	hsa-miR-16-5p	UAGCAGCACGUAAAUAUUGGCG	Hu, Ms, Rt	MIMAT0000069
24	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAG	Hu, Ms, Rt	MIMAT0000070
25	hsa-miR-181a-5p	AACAUUCAACGCUGUCGGUGAGU	Hu, Ms, Rt	MIMAT0000256
26	mmu-miR-182-5p	UUUGGCAAUGGUAGAACUCACACCG	Ms, Rt	MIMAT0000211
27	rno-miR-183-5p	UAUGGCACUGGUAGAAUUCACU	Hu, Ms, Rt	MIMAT0000860
28	hsa-miR-186-5p	CAAAGAAUUCUCCUUUUGGGCU	Hu, Ms, Rt	MIMAT0000456
29	hsa-miR-18a-5p	UAAGGUGCAUCUAGUGCAGAUAG	Hu, Ms, Rt	MIMAT0000072
30	hsa-miR-191-5p	CAACGGAAUCCCAAAAGCAGCUG	Hu, Ms, Rt	MIMAT0000440
31	hsa-miR-192-5p	CUGACCUAUGAAUUGACAGCC	Hu, Ms, Rt	MIMAT0000222
32	hsa-miR-194-5p	UGUAACAGCAACUCCAUGUGGA	Hu, Ms, Rt	MIMAT0000460
33	hsa-miR-19a-3p	UGUGCAAAUCUAUGCAAAACUGA	Hu, Ms, Rt	MIMAT0000073
34	hsa-miR-200a-3p	UAACACUGUCUGGUAACGAUGU	Hu, Ms, Rt	MIMAT0000682
35	hsa-miR-200c-3p	UAAUACUGCCGGGUAAUGAUGGA	Hu,Ms	MIMAT0000617
36	hsa-miR-203a-3p	GUGAAAUGUUUAGGACCACUAG	Hu, Ms, Rt	MIMAT0000264
37	hsa-miR-206	UGGAAUGUAAGGAAGUGUGUGG	Hu, Ms, Rt	MIMAT0000462
38	hsa-miR-20b-5p	CAAAGUGCUCAUAGUGCAGGUAG	Hu, Ms, Rt	MIMAT0001413
39	hsa-miR-210-3p	CUGUGCGUGUGACAGCGGCUGA	Hu, Ms, Rt	MIMAT0000267
40	mmu-miR-212-3p	UAACAGUCUCCAGUCACGGCCA	Ms, Rt	MIMAT0000659
41	hsa-miR-214-3p	ACAGCAGGCACAGACAGGCAGU	Hu,Ms	MIMAT0000271
42	hsa-miR-21-5p	UAGCUUAUCAGACUGAUGUUGA	Hu, Ms, Rt	MIMAT0000076
43	hsa-miR-218-5p	UUGUGCUUGAUCUAACCAUGU	Hu, Ms, Rt	MIMAT0000275
44	hsa-miR-223-3p	UGUCAGUUUGUCAAAUACCCCA	Hu,Ms	MIMAT0000280
45	hsa-miR-23b-3p	AUCACAUUGCCAGGGAUUACC	Hu, Ms, Rt	MIMAT0000418
46	hsa-miR-26b-5p	UUCAAGUAAUUCAGGAUAGGU	Hu, Ms, Rt	MIMAT0000083
47	hsa-miR-27a-3p	UUCACAGUGGCUAAGUUCCGC	Hu, Ms, Rt	MIMAT0000084
48	hsa-miR-29a-3p	UAGCACCAUCUGAAAUCGGUUA	Hu, Ms, Rt	MIMAT0000086
49	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG	Hu, Ms, Rt	MIMAT0000087
50	hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	Hu, Ms, Rt	MIMAT0000244
51	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC	Hu, Ms, Rt	MIMAT0000693
52	hsa-miR-320a	AAAAGCUGGGUUGAGAGGGCGA	Hu, Ms, Rt	MIMAT0000510
53	hsa-miR-342-3p	UCUCACACAGAAAUCGCACCCGU	Hu, Ms, Rt	MIMAT0000753
54	hsa-miR-34a-5p	UGGCAGUGUCUUAGCUGGUUGU	Hu, Ms, Rt	MIMAT0000255
55	hsa-miR-34c-5p	AGGCAGUGUAGUUAGCUGAUUGC	Hu, Ms, Rt	MIMAT0000686
56	mmu-miR-378a-3p	ACUGGACUUGGAGUCAGAAGG	Ms, Rt	MIMAT0003151
57	hsa-miR-409-3p	GAAUGUUGCUCGGUGAACCCCU	Hu,Ms	MIMAT0001639
58	hsa-miR-455-5p	UAUGUGCCUUUGGACUACAUCG	Hu, Ms, Rt	MIMAT0003150
59	hsa-miR-484	UCAGGCUCAGUCCCCUCCCGAU	Hu, Ms, Rt	MIMAT0002174
60	hsa-miR-486-5p	UCCUGUACUGAGCUGCCCCGAG	Hu, Ms, Rt	MIMAT0002177
61	mmu-miR-489-3p	AAUGACACCACAUAUAUGGCAGC	Ms, Rt	MIMAT0003112
62	hsa-miR-494-3p	UGAAACAUACACGGGAAACCUC	Hu,Ms	MIMAT0002816
63	hsa-miR-532-3p	CCUCCCACACCCAAGGCUUGCA	Hu, Ms, Rt	MIMAT0004780
64	hsa-miR-93-5p	CAAAGUGCUGUUCGUGCAGGUAG	Hu, Ms, Rt	MIMAT0000093
65	hsa-miR-98-5p	UGAGGUAGUAAGUUGUAUUGUU	Hu, Ms, Rt	MIMAT0000096
66	ath-mir167d	UGAAGCUGCCAGCAUGAUCUGG	Ath	MIMAT0000905
67	cel-mir-70-3p	UAAUACGUCGUUGGUGUUUCCAU	Cel	MIMAT0000042
68	oan-miR-7417-5p	UUCCCCACUCUGAGCACACAGC	Oan	MIMAT0028982
69	x-control	x-control	N/A
70	blank	blank	N/A

Platform
Multiplex

Storage instructions
Store at +4°C. Please refer to protocols.
Components 1 x 48 tests 1 x 96 tests
FirePlex^®Particle Mix (Circulating) 1 x 1750µl 1 x 3500µl

Components	1 x 48 tests	1 x 96 tests
FirePlex^®Particle Mix (Circulating)	1 x 1750µl	1 x 3500µl

品牌介绍

Abcam 位于英国的剑桥科学园，成立于1998年，专门生产和分销研究型抗体。在线目录 (www.abcam.cn) 已有超过 120,000 种抗体和试剂，并不断添加，供应予全球百多个国家。
为使研究员更容易找到蛋白质研究试剂产品，在2011并购了美国的 MitoSciences 公司，加强了免疫分析方面的产品供应；同年也并购了英国的 Ascent Scientific 公司，开展了生化试剂的供应。在2012年并购了美国的 Epitomics 公司，成为一家有领导地位的 RabMAbs® 供应商。
Abcam 的目标是给世界上最好的抗体建立最大的在线目录，为各地科学家提供尖端产品，成为各国科学界的重要伙伴，为所有产品提供技术支持来使客户获得预期的结果，为提供高质量的抗体来指向尽可能多的靶蛋白，尽所能在尽可能多的应用和物种中检测每种抗体。
Abcam 专注于特定的研究领域，包括肿瘤研究、心血管研究、染色质和基因调控研究、免疫学、内参对照、微生物学、神经科学、细胞核信号转导研究、RNAi 研究、干细胞研究、亚细胞标记物等。

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