Abcam/Y-27632 dihydrochloride, Rho kinase inhibitor (ab120129)/1/ab120129,Abcam,,Abcam,+,,Array.Array蚂蚁淘厂家直采.

产品名称：Abcam/Y-27632 dihydrochloride, Rho kinase inhibitor (ab120129)/1/ab120129

产品编号：ab120129

市场价：¥0.00

场地：美国(厂家直采)

产品分类：蛋白类>聚合物>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： Abcam

公司：Abcam

公司分类：

商品介绍

Product name
Y-27632 dihydrochloride, Rho kinase inhibitor
Description
Selective Rho kinase inhibitor
Biological description
Y-27632 is a research tool with a wide variety of biological effects, mainly used in the field of stem cell research for maintenance and differentiation.Commonly used as 3D growth matrix component; also a component of brain organoid differentiation media.
How others have used Y-27632 in their research:
Maintenance of tissue culture of iPSCs; 10 μM Y-27632 for 24 hr; Montefiori et al (2018)Reprogramming of breast cancer cells to induced progenitor-like cells (iPLs) ; 2 μM Y27632 ; Yuan et al (2018)Differentiation - Y-27632 enables human embryonic stem cells to survive and differentiate into cortical and basal telencephalic progenitors; Watanabe et al (2007)
*Also available in simple stock solutions (ab144494) - add 1 ml of water to get an exact, ready-to-use concentration.
Purity
>99%
CAS Number
129830-38-2
Chemical structure

Chemical name
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Molecular weight
320.26
Molecular formula
C₁₄H₂₁N₃O.2HCl
PubChem identifier
9901617
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overview
Soluble in water to 100 mM and in DMSO to 100mM
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
SMILES
Cl.Cl.O=C(Nc1ccncc1)[C@@H]2CC[C@H](CC2)[C@@H](C)N
Source
Synthetic
Research areas
- Cell Biology
- Apoptosis
- Intracellular
- Kinases
- Signal Transduction
- Cytoskeleton / ECM
- Cytoskeleton
- Microfilaments
- Actin etc
- Actin Assembly
- Signal Transduction
- Protein Phosphorylation
- Ser / Thr Kinases
- Other Kinases
- Signal Transduction
- Signaling Pathway
- G Protein Signaling
- Small G Proteins
- Ras Family
- Cell Biology
- Cell Cycle
- Cell Division
- Centromere
- Cancer
- Cell cycle
- Cell division
- Cancer
- Signal transduction
- Protein phosphorylation
- Serine/threonine kinases
- Other
- Biochemicals
- Product Range
- Just Add Water
- Biochemicals
- Chemical Type
- Biochemicals
- Biochemicals
- Pharmacology
- Enzymes
- Kinase
- Rho kinase
- Inhibitors
- Biochemicals
- Pharmacology
- Signaling
- Extracellular matrix & cell adhesion
- Rho kinase
- Biochemicals
- Pharmacology
- Signaling
- Stem Cells
- Other
- Biochemicals
- Research Area
- Cancer
- Extracellular matrix & cell adhesion
- Rho kinase

品牌介绍

Abcam 位于英国的剑桥科学园，成立于1998年，专门生产和分销研究型抗体。在线目录 (www.abcam.cn) 已有超过 120,000 种抗体和试剂，并不断添加，供应予全球百多个国家。
为使研究员更容易找到蛋白质研究试剂产品，在2011并购了美国的 MitoSciences 公司，加强了免疫分析方面的产品供应；同年也并购了英国的 Ascent Scientific 公司，开展了生化试剂的供应。在2012年并购了美国的 Epitomics 公司，成为一家有领导地位的 RabMAbs® 供应商。
Abcam 的目标是给世界上最好的抗体建立最大的在线目录，为各地科学家提供尖端产品，成为各国科学界的重要伙伴，为所有产品提供技术支持来使客户获得预期的结果，为提供高质量的抗体来指向尽可能多的靶蛋白，尽所能在尽可能多的应用和物种中检测每种抗体。
Abcam 专注于特定的研究领域，包括肿瘤研究、心血管研究、染色质和基因调控研究、免疫学、内参对照、微生物学、神经科学、细胞核信号转导研究、RNAi 研究、干细胞研究、亚细胞标记物等。

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